Collection Notes: Follow instructions located in the Saliva Test Kit (instructions and collection tubes are within the kit). Transport at room temperature.
Clinical Utility: Melatonin is primarily secreted during the dark (night) cycle. Levels drop dramatically after exposure to bright light. Melatonin binds to various proteins including Albumin. Patients with cancer frequently have decreased levels of Melatonin as do patients with impaired central nervous system function. Elevated levels can be found in sympathetic orthostatic hypotension. Melatonin has a stimulatory and suppressive feedback on Gonadotropin release depending on Melatonin levels. Altered levels of Melatonin have been reported with sleep disorders, jet lag, depression, stress, schizophrenia, hypothalamic amenorrhea, pregnancy, anorexia nervosa, immunological disorders, as well as sexual maturation during puberty.
Saliva (follow Kit instructions)
Ambient 7 Days
Refrigerated 60 Days
Frozen 1 Year
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