Collection Notes: Collect as a trough just before the next dose. Plasma should be physically separated from cells as soon as possible with a maximum limit of 2 hours from the time of collection. Centrifuge and physically separate the plasma using a plastic transfer pipette into a separate plastic transfer tube.
Clinical Utility: Phenobarbital is used for the long-term treatment of grand mal seizures and cortical focal seizures. Levels are monitored to assure adequate therapeutic levels are achieved and to avoid toxicity.
Plasma (1 mL), EDTA
Ambient 5 Days
Refrigerated 7 Days
Frozen 30 Days
Plasma (1 mL), Lithium Heparin
Ambient 5 Days
Refrigerated 7 Days
Frozen 30 Days
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